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uPAR-targeted optical near-infrared (NIR) fluorescence imaging and PET for image-guided surgery in head and neck cancer: proof-of-concept in orthotopic xenograft model
PURPOSE: Urokinase-like Plasminogen Activator Receptor (uPAR) is overexpressed in a variety of carcinoma types, and therefore represents an attractive imaging target. The aim of this study was to assess the feasibility of two uPAR-targeted probes for PET and fluorescence tumor imaging in a human xen...
Autores principales: | Christensen, Anders, Juhl, Karina, Persson, Morten, Charabi, Birgitte Wittenborg, Mortensen, Jann, Kiss, Katalin, Lelkaitis, Giedrius, Rubek, Niclas, von Buchwald, Christian, Kjær, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362495/ https://www.ncbi.nlm.nih.gov/pubmed/28039488 http://dx.doi.org/10.18632/oncotarget.14282 |
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