Detection fidelity of AR mutations in plasma derived cell-free DNA

Somatic genetic alterations including copy number and point mutations in the androgen receptor (AR) are associated with resistance to therapies targeting the androgen/AR axis in patients with metastatic castration resistant prostate cancer (mCRPC). Due to limitations associated with biopsying metast...

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Detalles Bibliográficos
Autores principales: Goldstein, Alexa, Toro, Patricia Valda, Lee, Justin, Silberstein, John L., Nakazawa, Mary, Waters, Ian, Cravero, Karen, Chu, David, Cochran, Rory L., Kim, Minsoo, Shinn, Daniel, Torquato, Samantha, Hughes, Robert M., Pallavajjala, Aparna, Carducci, Michael A., Paller, Channing J., Denmeade, Samuel R., Kressel, Bruce, Trock, Bruce J., Eisenberger, Mario A., Antonarakis, Emmanuel S., Park, Ben H., Hurley, Paula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362513/
https://www.ncbi.nlm.nih.gov/pubmed/28152506
http://dx.doi.org/10.18632/oncotarget.14926

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