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SerpinB3 upregulates the Cyclooxygenase-2 / β-Catenin positive loop in colorectal cancer

Colorectal cancer is characterized by aberrant Cyclooxigenase-2 (COX-2) and β-Catenin pathways. Recently, the protease inhibitor SerpinB3 has been described overexpressed in more advanced stages of this tumor. Aim of the study was to explore the possible relationship between these molecules in this...

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Detalles Bibliográficos
Autores principales: Terrin, Liliana, Agostini, Marco, Ruvoletto, Mariagrazia, Martini, Andrea, Pucciarelli, Salvatore, Bedin, Chiara, Nitti, Donato, Pontisso, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362519/
https://www.ncbi.nlm.nih.gov/pubmed/28178650
http://dx.doi.org/10.18632/oncotarget.14997

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