Revealing a Novel Otubain-Like Enzyme from Leishmania infantum with Deubiquitinating Activity toward K48-Linked Substrate

Deubiquitinating enzymes (DUBs) play an important role in regulating a variety of eukaryotic processes. In this context, exploring the role of deubiquitination in Leishmania infantum could be a promising alternative to search new therapeutic targets for leishmaniasis. Here we present the first chara...

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Detalles Bibliográficos
Autores principales: Azevedo, Clênia S., Guido, Bruna C., Pereira, Jhonata L., Nolasco, Diego O., Corrêa, Rafael, Magalhães, Kelly G., Motta, Flávia N., Santana, Jaime M., Grellier, Philippe, Bastos, Izabela M. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362604/
https://www.ncbi.nlm.nih.gov/pubmed/28386537
http://dx.doi.org/10.3389/fchem.2017.00013

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