Chaperones in Polyglutamine Aggregation: Beyond the Q-Stretch

Expanded polyglutamine (polyQ) stretches in at least nine unrelated proteins lead to inherited neuronal dysfunction and degeneration. The expansion size in all diseases correlates with age at onset (AO) of disease and with polyQ protein aggregation, indicating that the expanded polyQ stretch is the...

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Detalles Bibliográficos
Autores principales: Kuiper, E. F. E., de Mattos, Eduardo P., Jardim, Laura B., Kampinga, Harm H., Bergink, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362620/
https://www.ncbi.nlm.nih.gov/pubmed/28386214
http://dx.doi.org/10.3389/fnins.2017.00145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362620/
https://www.ncbi.nlm.nih.gov/pubmed/28386214
http://dx.doi.org/10.3389/fnins.2017.00145

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