Macrophage function in obesity-induced inflammation and insulin resistance

The steadily increasing obesity epidemic affects currently 30% of western populations and is causative for numerous disorders. It has been demonstrated that immune cells such as macrophages reside in or infiltrate metabolic organs under obese conditions and cause the so-called low-grade inflammation...

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Detalles Bibliográficos
Autores principales: Lauterbach, Mario A. R., Wunderlich, F. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362664/
https://www.ncbi.nlm.nih.gov/pubmed/28233125
http://dx.doi.org/10.1007/s00424-017-1955-5
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author Lauterbach, Mario A. R.
Wunderlich, F. Thomas
author_facet Lauterbach, Mario A. R.
Wunderlich, F. Thomas
author_sort Lauterbach, Mario A. R.
collection PubMed
description The steadily increasing obesity epidemic affects currently 30% of western populations and is causative for numerous disorders. It has been demonstrated that immune cells such as macrophages reside in or infiltrate metabolic organs under obese conditions and cause the so-called low-grade inflammation or metaflammation that impairs insulin action thus leading to the development of insulin resistance. Here, we report on data that specifically address macrophage biology/physiology in obesity-induced inflammation and insulin resistance.
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spelling pubmed-53626642017-04-04 Macrophage function in obesity-induced inflammation and insulin resistance Lauterbach, Mario A. R. Wunderlich, F. Thomas Pflugers Arch Invited Review The steadily increasing obesity epidemic affects currently 30% of western populations and is causative for numerous disorders. It has been demonstrated that immune cells such as macrophages reside in or infiltrate metabolic organs under obese conditions and cause the so-called low-grade inflammation or metaflammation that impairs insulin action thus leading to the development of insulin resistance. Here, we report on data that specifically address macrophage biology/physiology in obesity-induced inflammation and insulin resistance. Springer Berlin Heidelberg 2017-02-23 2017 /pmc/articles/PMC5362664/ /pubmed/28233125 http://dx.doi.org/10.1007/s00424-017-1955-5 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Invited Review
Lauterbach, Mario A. R.
Wunderlich, F. Thomas
Macrophage function in obesity-induced inflammation and insulin resistance
title Macrophage function in obesity-induced inflammation and insulin resistance
title_full Macrophage function in obesity-induced inflammation and insulin resistance
title_fullStr Macrophage function in obesity-induced inflammation and insulin resistance
title_full_unstemmed Macrophage function in obesity-induced inflammation and insulin resistance
title_short Macrophage function in obesity-induced inflammation and insulin resistance
title_sort macrophage function in obesity-induced inflammation and insulin resistance
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362664/
https://www.ncbi.nlm.nih.gov/pubmed/28233125
http://dx.doi.org/10.1007/s00424-017-1955-5
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