Cargando…
Proteoform Profile Mapping of the Human Serum Complement Component C9 Revealing Unexpected New Features of N-, O-, and C-Glycosylation
[Image: see text] The human complement C9 protein (∼65 kDa) is a member of the complement pathway. It plays an essential role in the membrane attack complex (MAC), which forms a lethal pore on the cellular surface of pathogenic bacteria. Here, we charted in detail the structural microheterogeneity o...
Autores principales: | Franc, Vojtech, Yang, Yang, Heck, Albert J. R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362742/ https://www.ncbi.nlm.nih.gov/pubmed/28221766 http://dx.doi.org/10.1021/acs.analchem.6b04527 |
Ejemplares similares
-
Comprehensive Proteoform Characterization of Plasma Complement Component C8αβγ by Hybrid Mass Spectrometry Approaches
por: Franc, Vojtech, et al.
Publicado: (2018) -
Similar Albeit
Not the Same: In-Depth Analysis of
Proteoforms of Human Serum, Bovine Serum, and Recombinant Human Fetuin
por: Lin, Yu-Hsien, et al.
Publicado: (2018) -
Charting the
Proteoform Landscape of Serum Proteins
in Individual Donors by High-Resolution Native Mass Spectrometry
por: Cramer, Dario A. T., et al.
Publicado: (2022) -
A wealth of genotype-specific proteoforms fine-tunes hemoglobin scavenging by haptoglobin
por: Tamara, Sem, et al.
Publicado: (2020) -
Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5
por: Doorduijn, Dennis J, et al.
Publicado: (2022)