Toward an Optimized Workflow for Middle-Down Proteomics

[Image: see text] Mass spectrometry (MS)-based proteomics workflows can crudely be classified into two distinct regimes, targeting either relatively small peptides (i.e., 0.7 kDa < M(w) < 3.0 kDa) or small to medium sized intact proteins (i.e., 10 kDa < M(w) < 30 kDa), respectively, term...

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Detalles Bibliográficos
Autores principales: Cristobal, Alba, Marino, Fabio, Post, Harm, van den Toorn, Henk W. P., Mohammed, Shabaz, Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362747/
https://www.ncbi.nlm.nih.gov/pubmed/28233997
http://dx.doi.org/10.1021/acs.analchem.6b03756

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