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Nicotine enhances alcohol intake and dopaminergic responses through β2* and β4* nicotinic acetylcholine receptors

Alcohol and nicotine are the most widely co-abused drugs. Both modify the activity of dopaminergic (DA) neurons of the Ventral Tegmental Area (VTA) and lead to an increase in DA release in the Nucleus Accumbens, thereby affecting the reward system. Evidences support the hypothesis that distinct nico...

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Detalles Bibliográficos
Autores principales: Tolu, Stefania, Marti, Fabio, Morel, Carole, Perrier, Carole, Torquet, Nicolas, Pons, Stephanie, de Beaurepaire, Renaud, Faure, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362818/
https://www.ncbi.nlm.nih.gov/pubmed/28332590
http://dx.doi.org/10.1038/srep45116