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Bioreactor mechanically guided 3D mesenchymal stem cell chondrogenesis using a biocompatible novel thermo-reversible methylcellulose-based hydrogel

Autologous chondrocyte implantation for cartilage repair represents a challenge because strongly limited by chondrocytes’ poor expansion capacity in vitro. Mesenchymal stem cells (MSCs) can differentiate into chondrocytes, while mechanical loading has been proposed as alternative strategy to induce...

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Detalles Bibliográficos
Autores principales: Cochis, A., Grad, S., Stoddart, M. J., Farè, S., Altomare, L., Azzimonti, B., Alini, M., Rimondini, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362895/
https://www.ncbi.nlm.nih.gov/pubmed/28332587
http://dx.doi.org/10.1038/srep45018