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Bioreactor mechanically guided 3D mesenchymal stem cell chondrogenesis using a biocompatible novel thermo-reversible methylcellulose-based hydrogel
Autologous chondrocyte implantation for cartilage repair represents a challenge because strongly limited by chondrocytes’ poor expansion capacity in vitro. Mesenchymal stem cells (MSCs) can differentiate into chondrocytes, while mechanical loading has been proposed as alternative strategy to induce...
Autores principales: | Cochis, A., Grad, S., Stoddart, M. J., Farè, S., Altomare, L., Azzimonti, B., Alini, M., Rimondini, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362895/ https://www.ncbi.nlm.nih.gov/pubmed/28332587 http://dx.doi.org/10.1038/srep45018 |
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