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Novel Model of Tendon Regeneration Reveals Distinct Cell Mechanisms Underlying Regenerative and Fibrotic Tendon Healing

To date, the cell and molecular mechanisms regulating tendon healing are poorly understood. Here, we establish a novel model of tendon regeneration using neonatal mice and show that neonates heal via formation of a ‘neo-tendon’ that differentiates along the tendon specific lineage with functional re...

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Detalles Bibliográficos
Autores principales: Howell, Kristen, Chien, Chun, Bell, Rebecca, Laudier, Damien, Tufa, Sara F., Keene, Douglas R., Andarawis-Puri, Nelly, Huang, Alice H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362908/
https://www.ncbi.nlm.nih.gov/pubmed/28332620
http://dx.doi.org/10.1038/srep45238