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miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cells

Activation of endogenous stem/progenitor cells to repair injured tissues is an ideal option for disease treatment. However, adult pancreatic progenitor cells remain in a quiescent state in vivo. Thus, it is difficult to stimulate proliferation and differentiation in these progenitor cells, and the c...

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Detalles Bibliográficos
Autores principales: Li, Xuyan, Zhang, Zhenwu, Li, Yunchao, Zhao, Yicheng, Zhai, Wenjun, Yang, Lin, Kong, Delin, Wu, Chunyan, Chen, Zhenbao, Teng, Chun-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362961/
https://www.ncbi.nlm.nih.gov/pubmed/28332553
http://dx.doi.org/10.1038/srep45002