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A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a multi-organ autoimmune disease characterized by skin fibrosis. Internal organ involvement is heterogeneous. It is unknown whether disease mechanisms are common across all involved affected tissues or if each manifestation has a distinct underlying pathology....

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Detalles Bibliográficos
Autores principales: Taroni, Jaclyn N., Greene, Casey S., Martyanov, Viktor, Wood, Tammara A., Christmann, Romy B., Farber, Harrison W., Lafyatis, Robert A., Denton, Christopher P., Hinchcliff, Monique E., Pioli, Patricia A., Mahoney, J. Matthew, Whitfield, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363043/
https://www.ncbi.nlm.nih.gov/pubmed/28330499
http://dx.doi.org/10.1186/s13073-017-0417-1