Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein

Lentiviral vectors (LVs) are a highly valuable tool for gene transfer currently exploited in basic, applied, and clinical studies. Their optimization is therefore very important for the field of vectorology and gene therapy. A key molecule for LV function is the envelope because it guides cell entry...

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Detalles Bibliográficos
Autores principales: Zucchelli, Eleonora, Pema, Monika, Stornaiuolo, Anna, Piovan, Claudia, Scavullo, Cinzia, Giuliani, Erica, Bossi, Sergio, Corna, Stefano, Asperti, Claudia, Bordignon, Claudio, Rizzardi, Gian-Paolo, Bovolenta, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363313/
https://www.ncbi.nlm.nih.gov/pubmed/28344996
http://dx.doi.org/10.1016/j.omtm.2017.01.002

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