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INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes

Integration of new DNA into cellular genomes mediates replication of retroviruses and transposons; integration reactions have also been adapted for use in human gene therapy. Tracking the distributions of integration sites is important to characterize populations of transduced cells and to monitor p...

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Detalles Bibliográficos
Autores principales:	Sherman, Eric, Nobles, Christopher, Berry, Charles C., Six, Emmanuelle, Wu, Yinghua, Dryga, Anatoly, Malani, Nirav, Male, Frances, Reddy, Shantan, Bailey, Aubrey, Bittinger, Kyle, Everett, John K., Caccavelli, Laure, Drake, Mary J., Bates, Paul, Hacein-Bey-Abina, Salima, Cavazzana, Marina, Bushman, Frederic D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363316/ https://www.ncbi.nlm.nih.gov/pubmed/28344990 http://dx.doi.org/10.1016/j.omtm.2016.11.002

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