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Methodological overview of systematic reviews to establish the evidence base for emergency general surgery

BACKGROUND: The evidence for treatment decision‐making in emergency general surgery has not been summarized previously. The aim of this overview was to review the quantity and quality of systematic review evidence for the most common emergency surgical conditions. METHODS: Systematic reviews of the...

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Autores principales: Savović, J., Blencowe, N., Blazeby, J., Strong, Sean, Howes, Noah, Chalmers, K., Whale, K., Crichton, J., Gould, L., Kariyawasam, S., Mason, J., Pegna, V., Richards, S., Rowlands, C., Stevens, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363346/
https://www.ncbi.nlm.nih.gov/pubmed/28295254
http://dx.doi.org/10.1002/bjs.10476
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author Savović, J.
Blencowe, N.
Blazeby, J.
Strong, Sean
Howes, Noah
Chalmers, K.
Whale, K.
Crichton, J.
Gould, L.
Kariyawasam, S.
Mason, J.
Pegna, V.
Richards, S.
Rowlands, C.
Stevens, D.
author_facet Savović, J.
Blencowe, N.
Blazeby, J.
Strong, Sean
Howes, Noah
Chalmers, K.
Whale, K.
Crichton, J.
Gould, L.
Kariyawasam, S.
Mason, J.
Pegna, V.
Richards, S.
Rowlands, C.
Stevens, D.
collection PubMed
description BACKGROUND: The evidence for treatment decision‐making in emergency general surgery has not been summarized previously. The aim of this overview was to review the quantity and quality of systematic review evidence for the most common emergency surgical conditions. METHODS: Systematic reviews of the most common conditions requiring unplanned admission and treatment managed by general surgeons were eligible for inclusion. The Centre for Reviews and Dissemination databases were searched to April 2014. The number and type (randomized or non‐randomized) of included studies and patients were extracted and summarized. The total number of unique studies was recorded for each condition. The nature of the interventions (surgical, non‐surgical invasive or non‐invasive) was documented. The quality of reviews was assessed using the AMSTAR checklist. RESULTS: The 106 included reviews focused mainly on bowel conditions (42), appendicitis (40) and gallstone disease (17). Fifty‐one (48·1 per cent) included RCTs alone, 79 (74·5 per cent) included at least one RCT and 25 (23·6 per cent) summarized non‐randomized evidence alone. Reviews included 727 unique studies, of which 30·3 per cent were RCTs. Sixty‐five reviews compared different types of surgical intervention and 27 summarized trials of surgical versus non‐surgical interventions. Fifty‐seven reviews (53·8 per cent) were rated as low risk of bias. CONCLUSION: This overview of reviews highlights the need for more and better research in this field.
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spelling pubmed-53633462017-04-06 Methodological overview of systematic reviews to establish the evidence base for emergency general surgery Savović, J. Blencowe, N. Blazeby, J. Strong, Sean Howes, Noah Chalmers, K. Whale, K. Crichton, J. Gould, L. Kariyawasam, S. Mason, J. Pegna, V. Richards, S. Rowlands, C. Stevens, D. Br J Surg Review BACKGROUND: The evidence for treatment decision‐making in emergency general surgery has not been summarized previously. The aim of this overview was to review the quantity and quality of systematic review evidence for the most common emergency surgical conditions. METHODS: Systematic reviews of the most common conditions requiring unplanned admission and treatment managed by general surgeons were eligible for inclusion. The Centre for Reviews and Dissemination databases were searched to April 2014. The number and type (randomized or non‐randomized) of included studies and patients were extracted and summarized. The total number of unique studies was recorded for each condition. The nature of the interventions (surgical, non‐surgical invasive or non‐invasive) was documented. The quality of reviews was assessed using the AMSTAR checklist. RESULTS: The 106 included reviews focused mainly on bowel conditions (42), appendicitis (40) and gallstone disease (17). Fifty‐one (48·1 per cent) included RCTs alone, 79 (74·5 per cent) included at least one RCT and 25 (23·6 per cent) summarized non‐randomized evidence alone. Reviews included 727 unique studies, of which 30·3 per cent were RCTs. Sixty‐five reviews compared different types of surgical intervention and 27 summarized trials of surgical versus non‐surgical interventions. Fifty‐seven reviews (53·8 per cent) were rated as low risk of bias. CONCLUSION: This overview of reviews highlights the need for more and better research in this field. John Wiley & Sons, Ltd 2017-03-14 2017-04 /pmc/articles/PMC5363346/ /pubmed/28295254 http://dx.doi.org/10.1002/bjs.10476 Text en © 2017 The Authors. BJS published by John Wiley & Sons Ltd on behalf of BJS Society Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Savović, J.
Blencowe, N.
Blazeby, J.
Strong, Sean
Howes, Noah
Chalmers, K.
Whale, K.
Crichton, J.
Gould, L.
Kariyawasam, S.
Mason, J.
Pegna, V.
Richards, S.
Rowlands, C.
Stevens, D.
Methodological overview of systematic reviews to establish the evidence base for emergency general surgery
title Methodological overview of systematic reviews to establish the evidence base for emergency general surgery
title_full Methodological overview of systematic reviews to establish the evidence base for emergency general surgery
title_fullStr Methodological overview of systematic reviews to establish the evidence base for emergency general surgery
title_full_unstemmed Methodological overview of systematic reviews to establish the evidence base for emergency general surgery
title_short Methodological overview of systematic reviews to establish the evidence base for emergency general surgery
title_sort methodological overview of systematic reviews to establish the evidence base for emergency general surgery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363346/
https://www.ncbi.nlm.nih.gov/pubmed/28295254
http://dx.doi.org/10.1002/bjs.10476
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