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Systemic RALA/iNOS Nanoparticles: A Potent Gene Therapy for Metastatic Breast Cancer Coupled as a Biomarker of Treatment

This study aimed to determine the therapeutic benefit of a nanoparticular formulation for the delivery of inducible nitric oxide synthase (iNOS) gene therapy in a model of breast cancer metastasis. Nanoparticles comprising a cationic peptide vector, RALA, and plasmid DNA were formulated and characte...

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Detalles Bibliográficos
Autores principales:	McCrudden, Cian M., McBride, John W., McCaffrey, Joanne, Ali, Ahlam A., Dunne, Nicholas J., Kett, Vicky L., Coulter, Jonathan A., Robson, Tracy, McCarthy, Helen O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363505/ https://www.ncbi.nlm.nih.gov/pubmed/28325291 http://dx.doi.org/10.1016/j.omtn.2016.12.010

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