Specific and Stable Suppression of HIV Provirus Expression In Vitro by Chimeric Zinc Finger DNA Methyltransferase 1

HIV-1 inserts its proviral DNA into the infected host cells, by which HIV proviral DNA can then be duplicated along with each cell division. Thus, provirus cannot be eradicated completely by current antiretroviral therapy. We have developed an innovative strategy to silence the HIV provirus by targe...

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Detalles Bibliográficos
Autores principales: Deng, Junxiao, Qu, Xiying, Lu, Panpan, Yang, Xinyi, Zhu, Yuqi, Ji, Haiyan, Wang, Yanan, Jiang, Zhengtao, Li, Xian, Zhong, Yangcheng, Yang, He, Pan, Hanyu, Young, Won-Bin, Zhu, Huanzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363508/
https://www.ncbi.nlm.nih.gov/pubmed/28325289
http://dx.doi.org/10.1016/j.omtn.2017.01.002

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