Engineering of PEDF-Expressing Primary Pigment Epithelial Cells by the SB Transposon System Delivered by pFAR4 Plasmids

Neovascular age-related macular degeneration (nvAMD) is characterized by choroidal blood vessels growing into the subretinal space, leading to retinal pigment epithelial (RPE) cell degeneration and vision loss. Vessel growth results from an imbalance of pro-angiogenic (e.g., vascular endothelial gro...

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Detalles Bibliográficos
Autores principales: Thumann, Gabriele, Harmening, Nina, Prat-Souteyrand, Cécile, Marie, Corinne, Pastor, Marie, Sebe, Attila, Miskey, Csaba, Hurst, Laurence D., Diarra, Sabine, Kropp, Martina, Walter, Peter, Scherman, Daniel, Ivics, Zoltán, Izsvák, Zsuzsanna, Johnen, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363513/
https://www.ncbi.nlm.nih.gov/pubmed/28325297
http://dx.doi.org/10.1016/j.omtn.2017.02.002

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