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Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells

Cobalt-containing metal-on-metal hip replacements are associated with adverse reactions to metal debris (ARMD), including inflammatory pseudotumours, osteolysis, and aseptic implant loosening. The exact cellular and molecular mechanisms leading to these responses are unknown. Cobaltions (Co(2+)) act...

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Detalles Bibliográficos
Autores principales:	Anjum, Sami A., Lawrence, Helen, Holland, James P., Kirby, John A., Deehan, David J., Tyson, Alison J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363524/ https://www.ncbi.nlm.nih.gov/pubmed/27835611 http://dx.doi.org/10.18632/oncotarget.13260

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