Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect

The extent of tumor oxygenation is an important factor contributing to the efficacy of radiation therapy (RTx). Interestingly, several preclinical studies have shown benefit of combining RTx with drugs that inhibit tumor blood vessel growth, i.e. angiostatic therapy. Recent findings show that proper...

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Detalles Bibliográficos
Autores principales: Kleibeuker, Esther A., Fokas, Emmanouil, Allen, Philip D., Kersemans, Veerle, Griffioen, Arjan W., Beech, John, Im, Jaehong H., Smart, Sean C., Castricum, Kitty C., van den Berg, Jaap, Schulkens, Iris A., Hill, Sally A., Harris, Adrian L., Slotman, Ben J., Verheul, Henk M., Muschel, Ruth J., Thijssen, Victor L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363534/
https://www.ncbi.nlm.nih.gov/pubmed/27780936
http://dx.doi.org/10.18632/oncotarget.12814

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