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Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

Human CUB and Sushi multiple domains 1 (CSMD1) is a membrane-bound complement inhibitor suggested to act as a putative tumor suppressor gene, since allelic loss of this region encompassing 8p23 including CSMD1 characterizes various malignancies. Here, we assessed the role of CSMD1 as a tumor suppres...

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Detalles Bibliográficos
Autores principales: Escudero-Esparza, Astrid, Bartoschek, Michael, Gialeli, Chrysostomi, Okroj, Marcin, Owen, Sioned, Jirström, Karin, Orimo, Akira, Jiang, Wen G., Pietras, Kristian, Blom, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363559/
https://www.ncbi.nlm.nih.gov/pubmed/27764775
http://dx.doi.org/10.18632/oncotarget.12729

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