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IL27 controls skin tumorigenesis via accumulation of ETAR-positive CD11b cells in the pre-malignant skin
Establishment of a permissive pre-malignant niche in concert with mutant stem are key triggers to initiate skin carcinogenesis. An understudied area of research is finding upstream regulators of both these triggers. IL27, a pleiotropic cytokine with both pro- and anti-inflammatory properties, was fo...
Autores principales: | Dibra, Denada, Mitra, Abhisek, Newman, Melissa, Xia, Xueqing, Keenan, Camille, Cutrera, Jeffry J., Mathis, J. Michael, Wang, Xiao-Jing, Myers, Jeffrey, Li, Shulin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363575/ https://www.ncbi.nlm.nih.gov/pubmed/27738312 http://dx.doi.org/10.18632/oncotarget.12581 |
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