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c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia

Aberrant activation of c-Myc plays an important oncogenic role via regulating a series of coding and non-coding genes in acute myeloid leukemia (AML). Histone deacetylases (HDACs) can remove acetyl group from histone and regulate gene expression via changing chromatin structure. Here, we found miR-4...

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Detalles Bibliográficos
Autores principales: Su, Rui, Gong, Jia-Nan, Chen, Ming-Tai, Song, Li, Shen, Chao, Zhang, Xin-Hua, Yin, Xiao-Lin, Ning, Hong-Mei, Liu, Bing, Wang, Fang, Ma, Yan-Ni, Zhao, Hua-Lu, Yu, Jia, Zhang, Jun-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363596/
https://www.ncbi.nlm.nih.gov/pubmed/27764807
http://dx.doi.org/10.18632/oncotarget.12679

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