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SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

Sirtuin 1 (SIRT1) regulates adipocyte and osteoblast differentiation. However, the underlying mechanism should be investigated. This study revealed that SIRT1 acts as a crucial repressor of adipogenesis. RNA-interference-mediated SIRT1 knockdown or genetic ablation enhances adipogenic potential, whe...

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Detalles Bibliográficos
Autores principales:	Zhou, Yuanfei, Song, Tongxing, Peng, Jie, Zhou, Zheng, Wei, Hongkui, Zhou, Rui, Jiang, Siwen, Peng, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363615/ https://www.ncbi.nlm.nih.gov/pubmed/27776347 http://dx.doi.org/10.18632/oncotarget.12774

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