Efficient generation of antigen-specific CTLs by the BAFF-activated human B Lymphocytes as APCs: a novel approach for immunotherapy

Efficient antigen presentation is indispensable for cytotoxic T lymphocyte (CTL)-mediated immunotherapy. B-lymphocytes propagated with CD40L have been developed as antigen-presenting cells (APCs), but this capacity needs further optimization. Here, we aimed to expand human B-lymphocytes on a large s...

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Detalles Bibliográficos
Autores principales: Yiwen, Zhang, Shilin, Gao, Yingshi, Chen, Lishi, Su, Baohong, Luo, Chao, Liu, Linghua, Li, Ting, Pan, Hui, Zhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363617/
https://www.ncbi.nlm.nih.gov/pubmed/27780916
http://dx.doi.org/10.18632/oncotarget.12792

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