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CREB1 directly activates the transcription of ribonucleotide reductase small subunit M2 and promotes the aggressiveness of human colorectal cancer
As the small subunit of Ribonucleotide reductase (RR), RRM2 displays a very important role in various critical cellular processes such as cell proliferation, DNA repair, and senescence, etc. Importantly, RRM2 functions like a tumor driver in most types of cancer but little is known about the regulat...
Autores principales: | Fang, Zejun, Lin, Aifen, Chen, Jiaoe, Zhang, Xiaomin, Liu, Hong, Li, Hongzhang, Hu, Yanyan, Zhang, Xia, Zhang, Jiangang, Qiu, Lanlan, Mei, Lingming, Shao, Jimin, Chen, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363643/ https://www.ncbi.nlm.nih.gov/pubmed/27801665 http://dx.doi.org/10.18632/oncotarget.12938 |
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