CREB1 directly activates the transcription of ribonucleotide reductase small subunit M2 and promotes the aggressiveness of human colorectal cancer

As the small subunit of Ribonucleotide reductase (RR), RRM2 displays a very important role in various critical cellular processes such as cell proliferation, DNA repair, and senescence, etc. Importantly, RRM2 functions like a tumor driver in most types of cancer but little is known about the regulat...

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Detalles Bibliográficos
Autores principales: Fang, Zejun, Lin, Aifen, Chen, Jiaoe, Zhang, Xiaomin, Liu, Hong, Li, Hongzhang, Hu, Yanyan, Zhang, Xia, Zhang, Jiangang, Qiu, Lanlan, Mei, Lingming, Shao, Jimin, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363643/
https://www.ncbi.nlm.nih.gov/pubmed/27801665
http://dx.doi.org/10.18632/oncotarget.12938

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