OvAd1, a Novel, Potent, and Selective Chimeric Oncolytic Virus Developed for Ovarian Cancer by 3D-Directed Evolution

Effective therapeutics for ovarian cancer continue to be urgently needed, particularly for chemotherapy-resistant cases. Here we present both a 3D-Matrigel culture-based expansion of our directed evolution method for generation of oncolytic virotherapies and two promising ovarian-cancer targeted onc...

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Detalles Bibliográficos
Autores principales: Kuhn, Irene, Bauzon, Maxine, Green, Nicola, Seymour, Len, Fisher, Kerry, Hermiston, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363728/
https://www.ncbi.nlm.nih.gov/pubmed/28345024
http://dx.doi.org/10.1016/j.omto.2016.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363728/
https://www.ncbi.nlm.nih.gov/pubmed/28345024
http://dx.doi.org/10.1016/j.omto.2016.12.001

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