Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising platform for cardiac studies in vitro, and possibly for tissue repair in humans. However, hiPSC-CM cells tend to retain morphology, metabolism, patterns of gene expression, and electrophysiology similar to that of...

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Detalles Bibliográficos
Autores principales: Werley, Christopher A., Chien, Miao-Ping, Gaublomme, Jellert, Shekhar, Karthik, Butty, Vincent, Yi, B. Alexander, Kralj, Joel M., Bloxham, Blox, Boyer, Laurie A., Regev, Aviv, Cohen, Adam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363803/
https://www.ncbi.nlm.nih.gov/pubmed/28333933
http://dx.doi.org/10.1371/journal.pone.0172671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363803/
https://www.ncbi.nlm.nih.gov/pubmed/28333933
http://dx.doi.org/10.1371/journal.pone.0172671

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