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Visualizing the structure of RNA-seq expression data using grade of membership models

Grade of membership models, also known as “admixture models”, “topic models” or “Latent Dirichlet Allocation”, are a generalization of cluster models that allow each sample to have membership in multiple clusters. These models are widely used in population genetics to model admixed individuals who h...

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Detalles Bibliográficos
Autores principales: Dey, Kushal K., Hsiao, Chiaowen Joyce, Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363805/
https://www.ncbi.nlm.nih.gov/pubmed/28333934
http://dx.doi.org/10.1371/journal.pgen.1006599