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Visualizing the structure of RNA-seq expression data using grade of membership models
Grade of membership models, also known as “admixture models”, “topic models” or “Latent Dirichlet Allocation”, are a generalization of cluster models that allow each sample to have membership in multiple clusters. These models are widely used in population genetics to model admixed individuals who h...
Autores principales: | Dey, Kushal K., Hsiao, Chiaowen Joyce, Stephens, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363805/ https://www.ncbi.nlm.nih.gov/pubmed/28333934 http://dx.doi.org/10.1371/journal.pgen.1006599 |
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