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Multi-scale model of drug induced adaptive resistance of Gram-negative bacteria to polymyxin B
The purpose of this report is to apply multi-scale modeling using the theory of physiologically structured populations (PSP) to develop a mathematical model for antimicrobial resistance based on a heterogeneous distribution of receptors and affinities among bacterial cells. The theory has been teste...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363806/ https://www.ncbi.nlm.nih.gov/pubmed/28334005 http://dx.doi.org/10.1371/journal.pone.0171834 |