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Complete mapping of viral escape from neutralizing antibodies

Identifying viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a high-throughput approach to quantify the selection that monoclonal antibodies exert on all single amino-acid mutations to a viral protein. Thi...

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Detalles Bibliográficos
Autores principales:	Doud, Michael B., Hensley, Scott E., Bloom, Jesse D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363992/ https://www.ncbi.nlm.nih.gov/pubmed/28288189 http://dx.doi.org/10.1371/journal.ppat.1006271

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