Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization

We propose a novel statistical framework for integrating the result from molecular quantitative trait loci (QTL) mapping into genome-wide genetic association analysis of complex traits, with the primary objectives of quantitatively assessing the enrichment of the molecular QTLs in complex trait-asso...

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Detalles Bibliográficos
Autores principales: Wen, Xiaoquan, Pique-Regi, Roger, Luca, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363995/
https://www.ncbi.nlm.nih.gov/pubmed/28278150
http://dx.doi.org/10.1371/journal.pgen.1006646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363995/
https://www.ncbi.nlm.nih.gov/pubmed/28278150
http://dx.doi.org/10.1371/journal.pgen.1006646

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