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Peroxiredoxin-6 Negatively Regulates Bactericidal Activity and NF-κB Activity by Interrupting TRAF6-ECSIT Complex

A TRAF6-ECSIT complex is crucial for the generation of mitochondrial reactive oxygen species (mROS) and nuclear factor-kappa B (NF-κB) activation induced by Toll-like receptor 4 (TLR4). Peroxiredoxin-6 (Prdx6) as a member of the peroxiredoxin family of antioxidant enzymes is involved in antioxidant...

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Detalles Bibliográficos
Autores principales:	Min, Yoon, Wi, Sae M., Shin, Dongwoo, Chun, Eunyoung, Lee, Ki-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364181/ https://www.ncbi.nlm.nih.gov/pubmed/28393051 http://dx.doi.org/10.3389/fcimb.2017.00094

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