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Calcium-Dependent and Synapsin-Dependent Pathways for the Presynaptic Actions of BDNF

We used cultured hippocampal neurons to determine the signaling pathways mediating brain-derived neurotrophic factor (BDNF) regulation of spontaneous glutamate and GABA release. BDNF treatment elevated calcium concentration in presynaptic terminals; this calcium signal reached a peak within 1 min an...

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Detalles Bibliográficos
Autores principales: Cheng, Qing, Song, Sang-Ho, Augustine, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364187/
https://www.ncbi.nlm.nih.gov/pubmed/28392759
http://dx.doi.org/10.3389/fncel.2017.00075