rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome

We herein report a case of capsular warning syndrome (CWS) that was successfully treated with recombinant tissue plasminogen activator (rt-PA). A 70-year-old woman had repeated stereotyped transient ischemic attacks (TIAs) of right hemiparesis and dysarthria. After hospitalization, argatroban, aspir...

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Autores principales: Fuseya, Yasuhiro, Kawamura, Miyuki, Matsuda, Eri, Takada, Kozue, Watanabe, Kiwamu, Fujitake, Junko, Nakaya, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364199/
https://www.ncbi.nlm.nih.gov/pubmed/28202868
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author Fuseya, Yasuhiro
Kawamura, Miyuki
Matsuda, Eri
Takada, Kozue
Watanabe, Kiwamu
Fujitake, Junko
Nakaya, Yoshifumi
author_facet Fuseya, Yasuhiro
Kawamura, Miyuki
Matsuda, Eri
Takada, Kozue
Watanabe, Kiwamu
Fujitake, Junko
Nakaya, Yoshifumi
author_sort Fuseya, Yasuhiro
collection PubMed
description We herein report a case of capsular warning syndrome (CWS) that was successfully treated with recombinant tissue plasminogen activator (rt-PA). A 70-year-old woman had repeated stereotyped transient ischemic attacks (TIAs) of right hemiparesis and dysarthria. After hospitalization, argatroban, aspirin, and cilostazol were started but were ineffective. Thirteen hours after the first episode of TIAs, severe symptoms occurred. Magnetic resonance imaging showed acute infarctions in the internal capsule to corona radiata, so we used rt-PA. Since then, the TIAs have not occurred, and the symptoms have considerably improved. This case suggests that rt-PA might be effective and safe for use in treating CWS.
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spelling pubmed-53641992017-03-24 rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome Fuseya, Yasuhiro Kawamura, Miyuki Matsuda, Eri Takada, Kozue Watanabe, Kiwamu Fujitake, Junko Nakaya, Yoshifumi Intern Med Case Report We herein report a case of capsular warning syndrome (CWS) that was successfully treated with recombinant tissue plasminogen activator (rt-PA). A 70-year-old woman had repeated stereotyped transient ischemic attacks (TIAs) of right hemiparesis and dysarthria. After hospitalization, argatroban, aspirin, and cilostazol were started but were ineffective. Thirteen hours after the first episode of TIAs, severe symptoms occurred. Magnetic resonance imaging showed acute infarctions in the internal capsule to corona radiata, so we used rt-PA. Since then, the TIAs have not occurred, and the symptoms have considerably improved. This case suggests that rt-PA might be effective and safe for use in treating CWS. The Japanese Society of Internal Medicine 2017-02-15 /pmc/articles/PMC5364199/ /pubmed/28202868 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Fuseya, Yasuhiro
Kawamura, Miyuki
Matsuda, Eri
Takada, Kozue
Watanabe, Kiwamu
Fujitake, Junko
Nakaya, Yoshifumi
rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome
title rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome
title_full rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome
title_fullStr rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome
title_full_unstemmed rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome
title_short rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome
title_sort rt-pa with antithrombotic therapies in a case with capsular warning syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364199/
https://www.ncbi.nlm.nih.gov/pubmed/28202868
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