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Elevated granzyme B(+) B-cell level in SIV-infection correlate with viral load and low CD4 T-cell count
Granzyme B-expressing (GrB(+)) B cells are thought to contribute to immune dysfunctions in HIV patients, but so far their exact role is unknown. This report demonstrates for the first time the existence of GrB(+) B cells in SIV-infected rhesus macaques, which represent the most commonly used nonhuma...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364320/ https://www.ncbi.nlm.nih.gov/pubmed/27779180 http://dx.doi.org/10.1038/icb.2016.96 |