Cargando…

Impact of T-cell-specific Smad4 deficiency on the development of autoimmune diabetes in NOD mice

Type 1 diabetes results from autoimmune-mediated pancreatic beta-cell destruction and transforming growth factor-beta (TGF-β) is known to play a preventive role in type 1 diabetes in non-obese diabetic (NOD) mice. In this study, we investigated the role of Smad4, a key molecule for Smad-dependent TG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Donghee, Lee, Song Mi, Jun, Hee-Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364321/ https://www.ncbi.nlm.nih.gov/pubmed/27686408 http://dx.doi.org/10.1038/icb.2016.98

Ejemplares similares

Smad4 in T cells plays a protective role in the development of autoimmune Sjögren's syndrome in the nonobese diabetic mouse
por: Kim, Donghee, et al.
Publicado: (2016)

Inhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice
por: Park, Eunhye, et al.
Publicado: (2017)

WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis
por: Ferris, Stephen T., et al.
Publicado: (2023)

Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice
por: Alkan, Manal, et al.
Publicado: (2015)

Deficiency of Nuclear Factor-κB c-Rel Accelerates the Development of Autoimmune Diabetes in NOD Mice
por: Ramakrishnan, Parameswaran, et al.
Publicado: (2016)

Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics
por: Kim, Tae Kang, et al.
Publicado: (2020)

Prevention of Autoimmune Diabetes in NOD Mice by Dimethyl Fumarate
por: Li, Shiri, et al.
Publicado: (2021)

Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice
por: Alibashe-Ahmed, Mohamed, et al.
Publicado: (2019)

TAK1 inhibition prevents the development of autoimmune diabetes in NOD mice
por: Cao, Hui, et al.
Publicado: (2015)

High‐fat diet prevents the development of autoimmune diabetes in NOD mice
por: Clark, Amy L., et al.
Publicado: (2021)

Development of Spontaneous Autoimmune Peripheral Polyneuropathy in B7-2–Deficient Nod Mice
por: Salomon, Benoît, et al.
Publicado: (2001)

T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
Publicado: (1989)

NK Cells Are Not Required for Spontaneous Autoimmune Diabetes in NOD Mice
por: Beilke, Joshua N., et al.
Publicado: (2012)

Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy
por: Wang, Duncheng, et al.
Publicado: (2015)

Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice
por: Jhala, Gaurang, et al.
Publicado: (2021)

Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice
Publicado: (1996)

Human milk oligosaccharides protect against the development of autoimmune diabetes in NOD-mice
por: Xiao, Ling, et al.
Publicado: (2018)

The NOD Mouse Beyond Autoimmune Diabetes
por: Aubin, Anne-Marie, et al.
Publicado: (2022)

Inhibition of Th17 Cells Regulates Autoimmune Diabetes in NOD Mice
por: Emamaullee, Juliet A., et al.
Publicado: (2009)

Nearby Construction Impedes the Progression to Overt Autoimmune Diabetes in NOD Mice
por: Hillhouse, Erin E., et al.
Publicado: (2013)

Effect of Arginase-1 Inhibition on the Incidence of Autoimmune Diabetes in NOD Mice
por: Hernandez, Luis F, et al.
Publicado: (2018)

Early Treatment of NOD Mice With B7-H4 Reduces the Incidence of Autoimmune Diabetes
por: Wang, Xiaojie, et al.
Publicado: (2011)

The Dual Role of Scavenger Receptor Class A in Development of Diabetes in Autoimmune NOD Mice
por: Shimizu, Mami, et al.
Publicado: (2014)

Molecular pathway alterations in CD4 T-cells of nonobese diabetic (NOD) mice in the preinsulitis phase of autoimmune diabetes
por: Kakoola, Dorothy N., et al.
Publicado: (2014)

IRAK-M Deficiency Promotes the Development of Type 1 Diabetes in NOD Mice
por: Tan, Qiyuan, et al.
Publicado: (2014)

Increased Autoimmune Diabetes in pIgR-Deficient NOD Mice Is Due to a "Hitchhiking" Interval that Refines the Genetic Effect of Idd5.4
por: Simpfendorfer, Kim R., et al.
Publicado: (2015)

Limited Effect of CpG ODN in Preventing Type 1 Diabetes in NOD Mice
por: Lee, Byong Jun, et al.
Publicado: (2005)

Targeting B-cells Mitigates Autoimmune Diabetes in NOD Mice: What Is Plan B?
por: Smith, Susan H., et al.
Publicado: (2009)

Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes
Publicado: (1992)

Genetic Deficiency of Itgb2 or ItgaL Prevents Autoimmune Diabetes Through Distinctly Different Mechanisms in NOD/LtJ Mice
por: Glawe, John D., et al.
Publicado: (2009)

Formation of Autoimmune Lesions Is Independent of Antibiotic Treatment in NOD Mice
por: Sato, Mami, et al.
Publicado: (2021)

The effect of spermidine on autoimmunity and beta cell function in NOD mice
por: Karacay, Ceren, et al.
Publicado: (2022)

The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice
por: Ansari, Mohammed Javeed I., et al.
Publicado: (2003)

Prevention of Autoimmune Diabetes and Induction of β-Cell Proliferation in NOD Mice by Hyperbaric Oxygen Therapy
por: Faleo, Gaetano, et al.
Publicado: (2012)

B cell–deficient NOD.H-2h4 mice have CD4(+)CD25(+) T regulatory cells that inhibit the development of spontaneous autoimmune thyroiditis
por: Yu, Shiguang, et al.
Publicado: (2006)

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse
por: Borg, Danielle J., et al.
Publicado: (2017)

The Spontaneous Autoimmune Neuromyopathy in ICOSL(−/−) NOD Mice Is CD4(+) T-Cell and Interferon-γ Dependent
por: Briet, Claire, et al.
Publicado: (2017)

SMAD4 Deficiency Leads to Development of Arteriovenous Malformations in Neonatal and Adult Mice
por: Kim, Yong Hwan, et al.
Publicado: (2018)

Glibenclamide Prevents Diabetes in NOD Mice
por: Lamprianou, Smaragda, et al.
Publicado: (2016)

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells
Publicado: (1987)

Cannot write session to /tmp/vufind_sessions/sess_lr42v5ukud6612c865m89nou2c