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Poly lactic-co-glycolic acid controlled delivery of disulfiram to target liver cancer stem-like cells

Disulfiram (DS), an anti-alcoholism drug, shows very strong cytotoxicity in many cancer types. However its clinical application in cancer treatment is limited by the very short half-life in the bloodstream. In this study, we developed a poly lactic-co-glycolic acid (PLGA)-encapsulated DS protecting...

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Detalles Bibliográficos
Autores principales:	Wang, Zhipeng, Tan, Jiao, McConville, Christopher, Kannappan, Vinodh, Tawari, Patricia Erebi, Brown, James, Ding, Jin, Armesilla, Angel L., Irache, Juan M., Mei, Qi-Bing, Tan, Yuhuan, Liu, Ying, Jiang, Wenguo, Bian, Xiu-Wu, Wang, Weiguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364371/ https://www.ncbi.nlm.nih.gov/pubmed/27521693 http://dx.doi.org/10.1016/j.nano.2016.08.001

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