Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation

Protein aggregation is associated with age-related neurodegenerative disorders, such as Alzheimer’s and polyglutamine diseases. As a causal relationship between protein aggregation and neurodegeneration remains elusive, understanding the cellular mechanisms regulating protein aggregation will help d...

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Detalles Bibliográficos
Autores principales: Sin, Olga, de Jong, Tristan, Mata-Cabana, Alejandro, Kudron, Michelle, Zaini, Mohamad Amr, Aprile, Francesco A., Seinstra, Renée I., Stroo, Esther, Prins, Roméo Willinge, Martineau, Céline N., Wang, Hai Hui, Hogewerf, Wytse, Steinhof, Anne, Wanker, Erich E., Vendruscolo, Michele, Calkhoven, Cornelis F., Reinke, Valerie, Guryev, Victor, Nollen, Ellen A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364375/
https://www.ncbi.nlm.nih.gov/pubmed/28306505
http://dx.doi.org/10.1016/j.molcel.2017.02.022

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