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Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis
Physical forces affect tumour growth, progression and metastasis. Here, we develop polymeric mechanical amplifiers that exploit in vitro and in vivo physical forces to increase immune cytokine-mediated tumour cell apoptosis. Mechanical amplifiers, consisting of biodegradable polymeric particles teth...
Autores principales: | Mitchell, Michael J., Webster, Jamie, Chung, Amanda, Guimarães, Pedro P. G., Khan, Omar F., Langer, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364380/ https://www.ncbi.nlm.nih.gov/pubmed/28317839 http://dx.doi.org/10.1038/ncomms14179 |
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