A natural tandem array alleviates epigenetic repression of IPA1 and leads to superior yielding rice

Super hybrid rice varieties with ideal plant architecture (IPA) have been critical in enhancing food security worldwide. However, the molecular mechanisms underlying their improved yield remain unclear. Here, we report the identification of a QTL, qWS8/ipa1-2D, in the super rice Yongyou12 (YY12) and...

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Autores principales: Zhang, Lin, Yu, Hong, Ma, Bin, Liu, Guifu, Wang, Jianjun, Wang, Junmin, Gao, Rongcun, Li, Jinjun, Liu, Jiyun, Xu, Jing, Zhang, Yingying, Li, Qun, Huang, Xuehui, Xu, Jianlong, Li, Jianming, Qian, Qian, Han, Bin, He, Zuhua, Li, Jiayang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364388/
https://www.ncbi.nlm.nih.gov/pubmed/28317902
http://dx.doi.org/10.1038/ncomms14789
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author Zhang, Lin
Yu, Hong
Ma, Bin
Liu, Guifu
Wang, Jianjun
Wang, Junmin
Gao, Rongcun
Li, Jinjun
Liu, Jiyun
Xu, Jing
Zhang, Yingying
Li, Qun
Huang, Xuehui
Xu, Jianlong
Li, Jianming
Qian, Qian
Han, Bin
He, Zuhua
Li, Jiayang
author_facet Zhang, Lin
Yu, Hong
Ma, Bin
Liu, Guifu
Wang, Jianjun
Wang, Junmin
Gao, Rongcun
Li, Jinjun
Liu, Jiyun
Xu, Jing
Zhang, Yingying
Li, Qun
Huang, Xuehui
Xu, Jianlong
Li, Jianming
Qian, Qian
Han, Bin
He, Zuhua
Li, Jiayang
author_sort Zhang, Lin
collection PubMed
description Super hybrid rice varieties with ideal plant architecture (IPA) have been critical in enhancing food security worldwide. However, the molecular mechanisms underlying their improved yield remain unclear. Here, we report the identification of a QTL, qWS8/ipa1-2D, in the super rice Yongyou12 (YY12) and related varieties. In-depth genetic molecular characterization of qWS8/ipa1-2D reveals that this newly identified QTL results from three distal naturally occurring tandem repeats upstream of IPA1, a key gene/locus previously shown to shape rice ideal plant architecture and greatly enhance grain yield. The qWS8/ipa1-2D locus is associated with reduced DNA methylation and a more open chromatin state at the IPA1 promoter, thus alleviating the epigenetic repression of IPA1 mediated by nearby heterochromatin. Our findings reveal that IPA traits can be fine-tuned by manipulating IPA1 expression and that an optimal IPA1 expression/dose may lead to an ideal yield, demonstrating a practical approach to efficiently design elite super rice varieties.
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spelling pubmed-53643882017-04-11 A natural tandem array alleviates epigenetic repression of IPA1 and leads to superior yielding rice Zhang, Lin Yu, Hong Ma, Bin Liu, Guifu Wang, Jianjun Wang, Junmin Gao, Rongcun Li, Jinjun Liu, Jiyun Xu, Jing Zhang, Yingying Li, Qun Huang, Xuehui Xu, Jianlong Li, Jianming Qian, Qian Han, Bin He, Zuhua Li, Jiayang Nat Commun Article Super hybrid rice varieties with ideal plant architecture (IPA) have been critical in enhancing food security worldwide. However, the molecular mechanisms underlying their improved yield remain unclear. Here, we report the identification of a QTL, qWS8/ipa1-2D, in the super rice Yongyou12 (YY12) and related varieties. In-depth genetic molecular characterization of qWS8/ipa1-2D reveals that this newly identified QTL results from three distal naturally occurring tandem repeats upstream of IPA1, a key gene/locus previously shown to shape rice ideal plant architecture and greatly enhance grain yield. The qWS8/ipa1-2D locus is associated with reduced DNA methylation and a more open chromatin state at the IPA1 promoter, thus alleviating the epigenetic repression of IPA1 mediated by nearby heterochromatin. Our findings reveal that IPA traits can be fine-tuned by manipulating IPA1 expression and that an optimal IPA1 expression/dose may lead to an ideal yield, demonstrating a practical approach to efficiently design elite super rice varieties. Nature Publishing Group 2017-03-20 /pmc/articles/PMC5364388/ /pubmed/28317902 http://dx.doi.org/10.1038/ncomms14789 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zhang, Lin
Yu, Hong
Ma, Bin
Liu, Guifu
Wang, Jianjun
Wang, Junmin
Gao, Rongcun
Li, Jinjun
Liu, Jiyun
Xu, Jing
Zhang, Yingying
Li, Qun
Huang, Xuehui
Xu, Jianlong
Li, Jianming
Qian, Qian
Han, Bin
He, Zuhua
Li, Jiayang
A natural tandem array alleviates epigenetic repression of IPA1 and leads to superior yielding rice
title A natural tandem array alleviates epigenetic repression of IPA1 and leads to superior yielding rice
title_full A natural tandem array alleviates epigenetic repression of IPA1 and leads to superior yielding rice
title_fullStr A natural tandem array alleviates epigenetic repression of IPA1 and leads to superior yielding rice
title_full_unstemmed A natural tandem array alleviates epigenetic repression of IPA1 and leads to superior yielding rice
title_short A natural tandem array alleviates epigenetic repression of IPA1 and leads to superior yielding rice
title_sort natural tandem array alleviates epigenetic repression of ipa1 and leads to superior yielding rice
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364388/
https://www.ncbi.nlm.nih.gov/pubmed/28317902
http://dx.doi.org/10.1038/ncomms14789
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