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An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells
Influenza virus utilizes host splicing machinery to process viral mRNAs expressed from both M and NS segments. Through genetic analysis and functional characterization, we here show that the NS segment of H7N9 virus contains a unique G540A substitution, located within a previously undefined exonic s...
Autores principales: | Huang, Xiaofeng, Zheng, Min, Wang, Pui, Mok, Bobo Wing-Yee, Liu, Siwen, Lau, Siu-Ying, Chen, Pin, Liu, Yen-Chin, Liu, Honglian, Chen, Yixin, Song, Wenjun, Yuen, Kwok-Yung, Chen, Honglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364394/ https://www.ncbi.nlm.nih.gov/pubmed/28323816 http://dx.doi.org/10.1038/ncomms14751 |
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