Cargando…

Stability and dynamics of membrane-spanning DNA nanopores

Recently developed DNA-based analogues of membrane proteins have advanced synthetic biology. A fundamental question is how hydrophilic nanostructures reside in the hydrophobic environment of the membrane. Here, we use multiscale molecular dynamics (MD) simulations to explore the structure, stability...

Descripción completa

Detalles Bibliográficos
Autores principales: Maingi, Vishal, Burns, Jonathan R., Uusitalo, Jaakko J., Howorka, Stefan, Marrink, Siewert J., Sansom, Mark S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364398/
https://www.ncbi.nlm.nih.gov/pubmed/28317903
http://dx.doi.org/10.1038/ncomms14784