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Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor

Reliable determination of binding kinetics and affinity of DNA hybridization and single-base mismatches plays an essential role in systems biology, personalized and precision medicine. The standard tools are optical-based sensors that are difficult to operate in low cost and to miniaturize for high-...

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Detalles Bibliográficos
Autores principales: Xu, Shicai, Zhan, Jian, Man, Baoyuan, Jiang, Shouzhen, Yue, Weiwei, Gao, Shoubao, Guo, Chengang, Liu, Hanping, Li, Zhenhua, Wang, Jihua, Zhou, Yaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364407/
https://www.ncbi.nlm.nih.gov/pubmed/28322227
http://dx.doi.org/10.1038/ncomms14902