Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice

Elevated circulating fatty acids (FAs) contribute to the development of obesity-associated metabolic complications such as insulin resistance (IR) and non-alcoholic fatty liver disease (NAFLD). Hence, reducing adipose tissue lipolysis to diminish the mobilization of FAs and lower their respective pl...

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Detalles Bibliográficos
Autores principales: Schweiger, Martina, Romauch, Matthias, Schreiber, Renate, Grabner, Gernot F., Hütter, Sabrina, Kotzbeck, Petra, Benedikt, Pia, Eichmann, Thomas O., Yamada, Sohsuke, Knittelfelder, Oskar, Diwoky, Clemens, Doler, Carina, Mayer, Nicole, De Cecco, Werner, Breinbauer, Rolf, Zimmermann, Robert, Zechner, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364409/
https://www.ncbi.nlm.nih.gov/pubmed/28327588
http://dx.doi.org/10.1038/ncomms14859

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