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The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss

Membrane-bound proteases are essential for epidermal integrity. Human airway trypsin-like protease 4 (HAT-L4) is a type II transmembrane serine protease. Currently, its biochemical property, cellular distribution and physiological function remain unknown. Here we examined HAT-L4 expression and funct...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiwei, Hu, Yae, Yan, Ruhong, Dong, Liang, Jiang, Yizhi, Zhou, Zhichao, Liu, Meng, Zhou, Tiantian, Dong, Ningzheng, Wu, Qingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364460/
https://www.ncbi.nlm.nih.gov/pubmed/28338078
http://dx.doi.org/10.1038/srep45262