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Superposition-free comparison and clustering of antibody binding sites: implications for the prediction of the nature of their antigen
We describe here a superposition free method for comparing the surfaces of antibody binding sites based on the Zernike moments and show that they can be used to quickly compare and cluster sets of antibodies. The clusters provide information about the nature of the bound antigen that, when combined...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364466/ https://www.ncbi.nlm.nih.gov/pubmed/28338016 http://dx.doi.org/10.1038/srep45053 |